Primary acinic cell carcinoma of the nasal septum: a case report and review of the literature

Acinic cell carcinoma arising in nasal cavity is a rare entity, and the number of reported cases is very limited in the English-language literature. The diagnosis is based entirely on histological evaluations. We report a primary acinic cell carcinoma in a 63-year-old female who had right nasal obstruction with hyposmia for the past 2 years. The tumor was found to be arising from the right posterior nasal septum and showed the classic feature of acinic cell carcinoma on light microscopic examination, and it was treated by surgical excision and regular follow-up. Although this tumor usually has a low grade behavior with the best survival rate of any salivary malignancy, the neoplasm not only may recur locally but may also metastasize. Awareness of these rarities is important to ensure the best patient care. Herein, the clinical, histopathological features, and the management of this lesion is presented with a brief review of the relevant literature.